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| カタログ番号 | HB800014 | ||||||||
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| 説明 |
Anti-EGR1 Polyclonal Antibody (HB800014) is a rabbit polyclonal antibody detecting EGR1 in ELISA, IHC, WB. Suitable for Mouse, Bovine, Cerdocyon thous, Coturnix japonica, and Danio rerio.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human EGR1 (Gln282-Ser433). | ||||||||
| ターゲット | Zinc finger protein Krox-24, EGR-1, Nerve growth factor-induced protein A, Early growth response protein 1, NGFI-A, KROX24, Transcription factor ETR103, ZNF225, Transcription factor Zif268, Zinc finger protein 225, EGR1, AT225 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P18146 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Early growth response protein 1 (EGR1) is a ~57 kDa protein. Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. 1. Hu, CT. et al. (2010) The FEBS journal 277, 1202-18. PMID: 20121949 2. Hashimoto, H. et al. (2014) Genes & development 28, 2304-13. PMID: 25258363 3. Zandarashvili, L. et al. (2015) FEBS letters 589, 1748-53. PMID: 25999311 | ||||||||
| 注意事項 | For research use only. |
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