

| Каталожный номер | HB800014 | ||||||||
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| Описание |
Anti-EGR1 Polyclonal Antibody (HB800014) is a rabbit polyclonal antibody detecting EGR1 in ELISA, IHC, WB. Suitable for Mouse, Bovine, Cerdocyon thous, Coturnix japonica, and Danio rerio.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human EGR1 (Gln282-Ser433). | ||||||||
| Цель | Zinc finger protein Krox-24, EGR-1, Nerve growth factor-induced protein A, Early growth response protein 1, NGFI-A, KROX24, Transcription factor ETR103, ZNF225, Transcription factor Zif268, Zinc finger protein 225, EGR1, AT225 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P18146 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Early growth response protein 1 (EGR1) is a ~57 kDa protein. Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. 1. Hu, CT. et al. (2010) The FEBS journal 277, 1202-18. PMID: 20121949 2. Hashimoto, H. et al. (2014) Genes & development 28, 2304-13. PMID: 25258363 3. Zandarashvili, L. et al. (2015) FEBS letters 589, 1748-53. PMID: 25999311 | ||||||||
| Примечание | For research use only. |
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