

| Numéro de catalogue | MP590014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-ELOVL3/CIG30 Polyclonal Antibody (MP590014) is a rabbit polyclonal antibody detecting ELOVL3 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| Reactivité des espèces | Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Mouse ELOVL3/CIG30 (Asp110-Ser167). | ||||||||
| Cible | 3-keto acyl-CoA synthase ELOVL3, ELOVL FA elongase 3, Elongation of very long chain fatty acids protein 3, CIG30, ELOVL3, Cold-inducible glycoprotein of 30 kDa, Very long chain 3-oxoacyl-CoA synthase 3, ELOVL fatty acid elongase 3, Very long chain 3-ketoacyl-CoA synthase 3 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | O35949 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Very long chain fatty acid elongase 3 (ELOVL3/CIG30) is a ~32 kDa protein. Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and unsaturated acyl-CoA substrates with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Participates in the formation of certain VLCFA and triglycerides in certain cells of the hair follicles and the sebaceous glands, required for skin barrier function. | ||||||||
| Note | For research use only. |
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