Anti-ENPP2 Polyclonal Antibody (HC423014)

Name: Anti-ENPP2 Polyclonal Antibody
Brand: abinScience
SKU: HC423014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HC423014

説明

Anti-ENPP2 Polyclonal Antibody (HC423014) is a rabbit polyclonal antibody detecting ENPP2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

ELISA, IHC, WB

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human ENPP2 (Ser637-Ile863).

ターゲット

LysoPLD, Extracellular lysophospholipase D, ENPP2, Ectonucleotide pyrophosphatase/phosphodiesterase family member 2, E-NPP 2, PDNP2, Autotaxin, ATX

精製

Purified by antigen affinity column.

アクセッション番号

Q13822

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Autotaxin (ENPP2) is a ~98 kDa protein. Secreted lysophospholipase D that hydrolyzes lysophospholipids to produce the signaling molecule lysophosphatidic acid (LPA) in extracellular fluids. Its major substrate is lysophosphatidylcholine. Can also act on sphingosylphosphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth.

1. Aoki, J. et al. (2002) The Journal of biological chemistry 277, 48737-44. PMID: 12354767

2. Clair, T. et al. (2003) Cancer research 63, 5446-53. PMID: 14500380

3. van Meeteren, LA. et al. (2005) The Journal of biological chemistry 280, 21155-61. PMID: 15769751

4. Stein, AJ. et al. (2015) Molecular pharmacology 88, 982-92. PMID: 26371182

5. Bain, G. et al. (2017) The Journal of pharmacology and experimental therapeutics 360, 1-13. PMID: 27754931

6. Tokumura, A. et al. (2002) The Journal of biological chemistry 277, 39436-42. PMID: 12176993

9. Bolen, AL. et al. (2011) Journal of lipid research 52, 958-70. PMID: 21393252

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-ENPP2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-ENPP2 Polyclonal Antibody (HC423014)

概要

イメージ

参考文献

データシート

SDS