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| カタログ番号 | HS760014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-FSCN1 Polyclonal Antibody (HS760014) is a rabbit polyclonal antibody detecting FSCN1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human FSCN1 (Gln277-Gly396). | ||||||||
| ターゲット | SNL, FAN1, Fascin, 55 kDa actin-bundling protein, p55, Singed-like protein, FSCN1, HSN | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | Q16658 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Fascin (FSCN1) is a ~54 kDa protein. Actin-binding protein that contains 2 major actin binding sites. Organizes filamentous actin into parallel bundles. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF. 1. Jansen, S. et al. (2011) The Journal of biological chemistry 286, 30087-96. PMID: 21685497 2. Yang, S. et al. (2013) The Journal of biological chemistry 288, 274-84. PMID: 23184945 3. Chen, L. et al. (2010) Nature 464, 1062-6. PMID: 20393565 4. Deinhardt, K. et al. (2011) Science signaling 4, ra82. PMID: 22155786 | ||||||||
| 注意事項 | For research use only. |
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