Anti-Human FSCN1 Monoclonal Antibody (1A596) (HS760035)

Name: Anti-Human FSCN1 Monoclonal Antibody (1A596)
Brand: abinScience
SKU: HS760035
Price: 106 USD
Availability: InStock

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Overview

Catalog No.	HS760035
Description	Anti-Human FSCN1 Monoclonal Antibody (1A596) [1A596] (HS760035) is a mouse monoclonal antibody detecting FSCN1 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A596
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human FSCN1 (Gln277-Gly396).
Target	Fascin, 55 kDa actin-bundling protein, Singed-like protein, p55, FSCN1
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q16658
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Fascin (FSCN1) is a ~54 kDa protein. Actin-binding protein that contains 2 major actin binding sites. Organizes filamentous actin into parallel bundles. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF. 1. Jansen, S. et al. (2011) The Journal of biological chemistry 286, 30087-96. PMID: 21685497 2. Yang, S. et al. (2013) The Journal of biological chemistry 288, 274-84. PMID: 23184945 3. Chen, L. et al. (2010) Nature 464, 1062-6. PMID: 20393565 4. Deinhardt, K. et al. (2011) Science signaling 4, ra82. PMID: 22155786
Note	For research use only.