Anti-FSCN1 Polyclonal Antibody (HS760014)

Name: Anti-FSCN1 Polyclonal Antibody
Brand: abinScience
SKU: HS760014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HS760014

Description

Anti-FSCN1 Polyclonal Antibody (HS760014) is a rabbit polyclonal antibody detecting FSCN1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human FSCN1 (Gln277-Gly396).

Target

SNL, FAN1, Fascin, 55 kDa actin-bundling protein, p55, Singed-like protein, FSCN1, HSN

Purification

Purified by antigen affinity column.

Accession

Q16658

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Fascin (FSCN1) is a ~54 kDa protein. Actin-binding protein that contains 2 major actin binding sites. Organizes filamentous actin into parallel bundles. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. Mediates reorganization of the actin cytoskeleton and axon growth cone collapse in response to NGF.

1. Jansen, S. et al. (2011) The Journal of biological chemistry 286, 30087-96. PMID: 21685497

2. Yang, S. et al. (2013) The Journal of biological chemistry 288, 274-84. PMID: 23184945

3. Chen, L. et al. (2010) Nature 464, 1062-6. PMID: 20393565

4. Deinhardt, K. et al. (2011) Science signaling 4, ra82. PMID: 22155786

Note

For research use only.

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References

Datasheet