Anti-G protein Recombinant Nanobody (Nb35) (HC114013)

Name: Anti-G protein Recombinant Nanobody (Nb35)
Brand: abinScience
SKU: HC114013
Price: 191 USD
Availability: InStock

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50ug
100ug
1mg

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Обзор
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Даташит
SDS

Обзор

Каталожный номер	HC114013
Описание	Anti-G protein Nanobody (Nb35) [Nb35] (HC114013) is a alpaca monoclonal antibody detecting G protein in Cyro-EM, X-ray Crystallography. Suitable for Human.
Реактивность видов	Human
Применения	Cyro-EM, X-ray Crystallography
Хозяинский вид	Alpaca
Клоональность	Monoclonal
Изотип	VHH-His
ID клона	Nb35
Цель	G protein
Уровень эндотоксинов	<0.01 EU/ug
Чистота	>95% as determined by SDS-PAGE.
Очистка	Purified by Nickel column.
Номер доступа	P63092
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Альтернативные названия	Nanobody 35, Nanobody-35, Nb-35
Фон	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short is a ~45 kDa protein. Guanine nucleotide-binding proteins (G proteins) function as transducers in numerous signaling pathways controlled by G protein-coupled receptors (GPCRs). The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins. 1. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161 2. Gao, X. et al. (2007) The Journal of biological chemistry 282, 294-302. PMID: 17110384 3. Thiele, S. et al. (2011) Human mutation 32, 653-60. PMID: 21488135 4. Brand, CS. et al. (2015) Molecular pharmacology 88, 758-67. PMID: 26206488 5. Farfel, Z. et al. (1996) The Journal of biological chemistry 271, 19653-5. PMID: 8702665 6. Warner, DR. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 4268-72. PMID: 10200251
Примечание	For research use only

Изображения

SDS-PAGE

SDS-PAGE for Anti-G protein Nanobody (Nb35)

Ссылки

Даташит

Anti-G protein Recombinant Nanobody (Nb35).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Volume

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Formula

C₁ × V₁ = C₂ × V₂

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Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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