

| Numéro de catalogue | HX950014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-GP2 Polyclonal Antibody (HX950014) is a rabbit polyclonal antibody detecting GP2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Reactivité des espèces | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human GP2 (Phe307-Asn512). | ||||||||
| Cible | Pancreatic zymogen granule membrane protein GP-2, GP2, ZAP75, Pancreatic secretory granule membrane major glycoprotein GP2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P55259 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Pancreatic secretory granule membrane major glycoprotein GP2 is a ~59 kDa protein. Functions as an intestinal M-cell transcytotic receptor specific for type-I-piliated bacteria that participates in the mucosal immune response toward these bacteria. At the apical membrane of M-cells it binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to elicit a mucosal immune response. | ||||||||
| Note | For research use only. |




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