Anti-Human GP2 Monoclonal Antibody (1A657) (HX950025)

Name: Anti-Human GP2 Monoclonal Antibody (1A657)
Brand: abinScience
SKU: HX950025
Price: 106 USD
Availability: InStock

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Overview

Catalog No.	HX950025
Description	Anti-Human GP2 Monoclonal Antibody (1A657) [1A657] (HX950025) is a mouse monoclonal antibody detecting GP2 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A657
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human GP2 (Phe307-Asn512).
Target	Pancreatic secretory granule membrane major glycoprotein GP2, Pancreatic zymogen granule membrane protein GP-2, ZAP75, GP2
Purification	Protein A/G purified from cell culture supernatant.
Accession	P55259
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	Pancreatic secretory granule membrane major glycoprotein GP2 is a ~59 kDa protein. Functions as an intestinal M-cell transcytotic receptor specific for type-I-piliated bacteria that participates in the mucosal immune response toward these bacteria. At the apical membrane of M-cells it binds fimH, a protein of the bacteria type I pilus tip. Internalizes bound bacteria, like E.coli and S.typhimurium, from the lumen of the intestine and delivers them, through M-cells, to the underlying organized lymphoid follicles where they are captured by antigen-presenting dendritic cells to elicit a mucosal immune response.
Note	For research use only.