Anti-GTPBP1 Polyclonal Antibody (HA399014)

Name: Anti-GTPBP1 Polyclonal Antibody
Brand: abinScience
SKU: HA399014
Price: 168 USD
Availability: InStock

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号

HA399014

説明

Anti-GTPBP1 Polyclonal Antibody (HA399014) is a rabbit polyclonal antibody detecting GTPBP1 in WB, IHC, ELISA. Suitable for Human, Mouse, Rat, Bovine, and .

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

種反応性

Human, Mouse, Rat

アプリケーション

WB, IHC, ELISA

宿主種

Rabbit

クローン性

Polyclonal

アイソタイプ

IgG

免疫原

E. coli - derived recombinant Human GTPBP1 (Thr71-Ser384).

ターゲット

GTPBP1

エンドトキシンレベル

Please contact with the lab for this information.

純度

>95% purity as determined by SDS-PAGE.

精製

Purified by antigen affinity column.

アクセッション番号

O00178

形態

Liquid

保存バッファー

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

製品使用情報

アプリケーション	希釈
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

安定性と保存

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

別名

GTPBP1, GTP-binding protein 1, G-protein 1, GP-1, GP1, GTPBP1

背景

GTP-binding protein 1 (GTPBP1) is a ~72 kDa protein. GTPase that plays a role in the elongation phase of protein synthesis by forming ternary complexes with GTP and aminoacyl-transfer RNAs (aa-tRNAs), and delivering aa-tRNAs to the ribosomal A site in a GTP-dependent manner. Is also able to deliver deacylated tRNA to the A site. Additionally, it is involved in RNA quality control; after GTP hydrolysis, which is not immediately followed by rapid peptide bond formation, GTPBP1 likely retains aa-tRNA in the A site and promotes exosomal degradation of faulty mRNAs engaged in 80S elongation complexes. Plays a role in the regulation of circadian mRNA stability.

1. Zinoviev, A. et al. (2018) Genes & development 32, 1226-1241. PMID: 30108131

注意事項

For research use only.

イメージ

参考文献

データシート

Anti-GTPBP1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

組換えタンパク質

抗体

アッセイキット

Anti-GTPBP1 Polyclonal Antibody (HA399014)

概要

イメージ

参考文献

データシート

SDS