

| Каталожный номер | HA399014 | ||||||||
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| Описание |
Anti-GTPBP1 Polyclonal Antibody (HA399014) is a rabbit polyclonal antibody detecting GTPBP1 in WB, IHC, ELISA. Suitable for Human, Mouse, Rat, Bovine, and .
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | WB, IHC, ELISA | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human GTPBP1 (Thr71-Ser384). | ||||||||
| Цель | GTPBP1 | ||||||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||||||
| Чистота | >95% purity as determined by SDS-PAGE. | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | O00178 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Альтернативные названия | GTPBP1, GTP-binding protein 1, G-protein 1, GP-1, GP1, GTPBP1 | ||||||||
| Фон | GTP-binding protein 1 (GTPBP1) is a ~72 kDa protein. GTPase that plays a role in the elongation phase of protein synthesis by forming ternary complexes with GTP and aminoacyl-transfer RNAs (aa-tRNAs), and delivering aa-tRNAs to the ribosomal A site in a GTP-dependent manner. Is also able to deliver deacylated tRNA to the A site. Additionally, it is involved in RNA quality control; after GTP hydrolysis, which is not immediately followed by rapid peptide bond formation, GTPBP1 likely retains aa-tRNA in the A site and promotes exosomal degradation of faulty mRNAs engaged in 80S elongation complexes. Plays a role in the regulation of circadian mRNA stability. 1. Zinoviev, A. et al. (2018) Genes & development 32, 1226-1241. PMID: 30108131 | ||||||||
| Примечание | For research use only. |
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