Anti-HAT1 Polyclonal Antibody (HD437014)

Name: Anti-HAT1 Polyclonal Antibody
Brand: abinScience
SKU: HD437014
Price: 96 USD
Availability: InStock

Даташит Поделиться продуктом Копировать информацию

Цена(USD): --

Спецификация:

20ug
50ug
100ug

Количество:

Свяжитесь с нами

Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HD437014

Описание

Anti-HAT1 Polyclonal Antibody (HD437014) is a rabbit polyclonal antibody detecting HAT1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human HAT1 (Met1-Glu419).

Цель

EC:2.3.1.48, HAT1, Histone acetyltransferase 1, Histone acetyltransferase type B catalytic subunit, KAT1

Уровень эндотоксинов

Please contact with the lab for this information.

Очистка

Purified by antigen affinity column.

Номер доступа

O14929

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Альтернативные названия

O14929

Фон

Histone acetyltransferase type B catalytic subunit (HAT1) is a ~49 kDa protein. Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac). Drives H4 production by chromatin binding to support chromatin replication and acetylation. Since transcription of H4 genes is tightly coupled to S-phase, plays an important role in S-phase entry and progression.

1. Campos, EI. et al. (2010) Nature structural & molecular biology 17, 1343-51. PMID: 20953179

2. Yang, X. et al. (2013) The Journal of biological chemistry 288, 18271-82. PMID: 23653357

3. Gruber, JJ. et al. (2019) Molecular cell 75, 711-724.e5. PMID: 31278053

4. Agudelo Garcia, PA. et al. (2020) Journal of proteome research 19, 1663-1673. PMID: 32081014

5. Makowski, AM. et al. (2001) The Journal of biological chemistry 276, 43499-502. PMID: 11585814

6. Wu, H. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, 8925-30. PMID: 22615379

7. Yuan, Y. et al. (2020) Molecular cell 77, 734-747.e7. PMID: 31812350

Примечание

For research use only

Изображения

Western blot

Western blot analysis was performed using anti-HAT1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: MDA-MB-231 cell lysate
Lane 2: Hela cell lysate
Lane 3: HepG2 cell lysate
Lane 4: 293T cell lysate
Lane 5: Lncap cell lysate
Lane 6: K562 cell lysate
Lane 7: PC-12 cell lysate

Ссылки

Даташит

Anti-HAT1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-HAT1 Polyclonal Antibody (HD437014)

Обзор

Изображения

Ссылки

Даташит

SDS