

| カタログ番号 | HW293014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 説明 |
Anti-HCFC1 Polyclonal Antibody (HW293014) is a rabbit polyclonal antibody detecting HCFC1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 種反応性 | Human, Mouse, Rat | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human HCFC1 (Asn52-His258). | ||||||||
| ターゲット | CFF, VCAF, HCFC1, HCF-1, HCF1, HFC1, C1 factor, HCF, VP16 accessory protein, Host cell factor 1 | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P51610 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Host cell factor 1 (HCFC1) is a ~208 kDa protein. Transcriptional coregulator. Serves as a scaffold protein, bridging interactions between transcription factors, including THAP11 and ZNF143, and transcriptional coregulators. Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300. Coactivator for EGR2 and GABP2. 1. Vinckevicius, A. et al. (2015) Molecular and cellular biology 35, 4135-46. PMID: 26416877 2. Mahajan, SS. et al. (2000) Molecular and cellular biology 20, 919-28. PMID: 10629049 3. Scarr, RB. et al. (2000) Molecular and cellular biology 20, 3568-75. PMID: 10779346 4. Khurana, B. et al. (2004) The Journal of biological chemistry 279, 33673-83. PMID: 15190068 5. Vogel, JL. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 6817-22. PMID: 16624878 6. Zhou, P. et al. (2013) The Journal of biological chemistry 288, 17532-43. PMID: 23629655 7. Vogel, JL. et al. (2000) The EMBO journal 19, 683-90. PMID: 10675337 8. Piluso, D. et al. (2002) The Journal of biological chemistry 277, 46799-808. PMID: 12244100 9. Luciano, RL. et al. (2003) The Journal of biological chemistry 278, 51116-24. PMID: 14532282 10. Wysocka, J. et al. (2003) Genes & development 17, 896-911. PMID: 12670868 | ||||||||
| 注意事項 | For research use only. |
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