

| Каталожный номер | HW293014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Описание |
Anti-HCFC1 Polyclonal Antibody (HW293014) is a rabbit polyclonal antibody detecting HCFC1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| Реактивность видов | Human, Mouse, Rat | ||||||||
| Применения | ELISA, IHC, WB | ||||||||
| Хозяинский вид | Rabbit | ||||||||
| Клоональность | Polyclonal | ||||||||
| Изотип | IgG | ||||||||
| Иммуноген | E. coli - derived recombinant Human HCFC1 (Asn52-His258). | ||||||||
| Цель | CFF, VCAF, HCFC1, HCF-1, HCF1, HFC1, C1 factor, HCF, VP16 accessory protein, Host cell factor 1 | ||||||||
| Очистка | Purified by antigen affinity column. | ||||||||
| Номер доступа | P51610 | ||||||||
| Форма | Liquid | ||||||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Фон | Host cell factor 1 (HCFC1) is a ~208 kDa protein. Transcriptional coregulator. Serves as a scaffold protein, bridging interactions between transcription factors, including THAP11 and ZNF143, and transcriptional coregulators. Involved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300. Coactivator for EGR2 and GABP2. 1. Vinckevicius, A. et al. (2015) Molecular and cellular biology 35, 4135-46. PMID: 26416877 2. Mahajan, SS. et al. (2000) Molecular and cellular biology 20, 919-28. PMID: 10629049 3. Scarr, RB. et al. (2000) Molecular and cellular biology 20, 3568-75. PMID: 10779346 4. Khurana, B. et al. (2004) The Journal of biological chemistry 279, 33673-83. PMID: 15190068 5. Vogel, JL. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 6817-22. PMID: 16624878 6. Zhou, P. et al. (2013) The Journal of biological chemistry 288, 17532-43. PMID: 23629655 7. Vogel, JL. et al. (2000) The EMBO journal 19, 683-90. PMID: 10675337 8. Piluso, D. et al. (2002) The Journal of biological chemistry 277, 46799-808. PMID: 12244100 9. Luciano, RL. et al. (2003) The Journal of biological chemistry 278, 51116-24. PMID: 14532282 10. Wysocka, J. et al. (2003) Genes & development 17, 896-911. PMID: 12670868 | ||||||||
| Примечание | For research use only. |
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