Anti-HCMV/HHV5 HHRF3/US28 Recombinant Nanobody (SAA1150) (VK595013)

Name: Anti-HCMV/HHV5 HHRF3/US28 Recombinant Nanobody (SAA1150)
Brand: abinScience
SKU: VK595013
Price: 126 USD
Availability: InStock

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1mg

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Изображения
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SDS

Обзор

Каталожный номер

VK595013

Описание

Anti-HCMV/HHV5 HHRF3/US28 Nanobody (SAA1150) [SAA1150] (VK595013) is a alpaca monoclonal antibody detecting HHRF3 in ELISA.

Реактивность видов

Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)

Применения

ELISA

Хозяинский вид

Alpaca

Клоональность

Monoclonal

Изотип

VHH-8His-Cys-tag

ID клона

SAA1150

Цель

G-protein coupled receptor homolog US28, HHRF3, US28

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Purified by Nickel column.

Номер доступа

P69333

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

G-protein coupled receptor homolog US28 (HHRF3) is a ~41 kDa protein. Viral chemokine receptor that plays a critical role in viral pathogenesis, mediating several processes such as cellular migration, differentiation, transformation, and viral latency and reactivation. Binds to a great number of different CC-chemokines including CCL5/RANTES, CCL2/MCP-1, CCL3/MIP-1-alpha as well as CX3CL1/Fractalkine. Transduces signals resulting in the activation of MAP kinase signaling pathways and augmentation of intracellular calcium ion levels, leading to alterations in chemotactic behavior of vascular smooth muscle cells and macrophages. The US28 receptor also exhibits high levels of agonist-independent signaling activity and agonist-independent endocytosis. Interacts with the host Gi complex without activating it, thereby probably interfering with the chemokine-Gi signaling.

1. Miles, TF. et al. (2018) eLife 7. PMID: 29882741

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-HCMV/HHV5 HHRF3/US28 Nanobody (SAA1150).

Ссылки

Даташит

Anti-HCMV/HHV5 HHRF3/US28 Recombinant Nanobody (SAA1150).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

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