

| Número de catálogo | VK681173 | ||||
|---|---|---|---|---|---|
| Reactividad de especies | Hepatitis C Virus (HCV) | ||||
| Aplicaciones | ELISA, Neutralization | ||||
| Especie huésped | Human | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG1, kappa | ||||
| ID de clon | B12.F8 | ||||
| Objetivo | Envelope glycoprotein E2, NS1, gp68, gp70 | ||||
| Nivel de endotoxinas | < 10 EU/mg | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | P27958 | ||||
| RRID | Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (B12.F8) (abinScience Cat# VK681173, RRID:AB_3725297) |
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| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Fondo | Genome polyprotein (NS1/gp68) is a ~327 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable). 1. Ivanyi-Nagy, R. et al. (2008) Nucleic acids research 36, 712-25. PMID: 18033802 2. Anjum, S. et al. (2013) Molecular medicine reports 8, 487-92. PMID: 23799612 3. Kittlesen, DJ. et al. (2000) The Journal of clinical investigation 106, 1239-49. PMID: 11086025 4. Waggoner, SN. et al. (2007) Journal of leukocyte biology 82, 1407-19. PMID: 17881511 5. Ruggieri, A. et al. (2003) Virus research 97, 103-10. PMID: 14602201 | ||||
| Nota | For research use only. |

SDS-PAGE for Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (B12.F8)




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