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Anti-HHV-5/HCMV UL83 Polyclonal Antibody (VK643014)

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Aperçu
Numéro de catalogueVK643014
Description
Anti-HHV-5/HCMV UL83 Polyclonal Antibody (VK643014) is a rabbit polyclonal antibody detecting UL83. Suitable for Human cytomegalovirus.
Reactivité des espècesHuman cytomegalovirus (HCMV) (HHV-5) (Human herpesvirus 5)
ApplicationsELISA, IHC, WB
Espèce hôteRabbit
ClonalitéPolyclonal
IsotypeIgG
Immunogène E. coli - derived recombinant HHV-5/HCMV UL83 (Thr297-Tyr510).
Cible 65 kDa matrix phosphoprotein, 65 kDa phosphoprotein, Phosphoprotein UL83, Tegument protein UL83, UL83, pp65
Niveau d'endotoxines Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Numéro d'accès P06725
Forme Liquid
Tampon de stockage 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Contexte

65 kDa phosphoprotein (UL83) is a ~62 kDa protein. Counteracts the host antiviral immune response when activated and phosphorylated, by preventing host IRF3 from entering the nucleus. Also inhibits the type I interferon production by inactivating the enzymatic activity of DNA sensor CGAS without affecting STING1. Participates in the transactivation of viral major immediate-early genes by the recruitment of host IFI16 to the promoters pf these genes.

1. Abate, DA. et al. (2004) Journal of virology 78, 10995-1006. PMID: 15452220
2. Biolatti, M. et al. (2018) Journal of virology 92. PMID: 29263269
3. Cox, JB. et al. (2025) Journal of virology 99, e0048125. PMID: 40243337
4. Cristea, IM. et al. (2010) Journal of virology 84, 7803-14. PMID: 20504932
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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