

| Каталожный номер | VK658024 | ||||
|---|---|---|---|---|---|
| Описание |
Anti-HPV16 L2 Polyclonal Antibody (VK658024) is a rabbit polyclonal antibody detecting HPV16 L2 in ELISA, IHC, WB.
Highlights
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| Реактивность видов | Human papillomavirus 16 (HPV16) | ||||
| Применения | ELISA, IHC, WB | ||||
| Хозяинский вид | Rabbit | ||||
| Клоональность | Polyclonal | ||||
| Изотип | IgG | ||||
| Иммуноген | E. coli - derived recombinant HPV16 L2 (Arg2-Ala473(Glu43Asp)). | ||||
| Цель | Minor capsid protein L2, L2 | ||||
| Уровень эндотоксинов | Please contact with the lab for this information. | ||||
| Очистка | Purified by antigen affinity column. | ||||
| Номер доступа | P03107 | ||||
| Форма | Liquid | ||||
| Буфер хранения | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
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| Информация об использовании продукта |
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| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Фон | Minor capsid protein L2 is a ~50 kDa protein. Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers. Plays a role in capsid stabilization through interaction with the major capsid protein L1. Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network. Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network. Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus. | ||||
| Примечание | For research use only |




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