Anti-HPV16 Minor capsid protein L2 Recombinant Antibody (MAb24B) (VK658013)

Name: Anti-HPV16 Minor capsid protein L2 Recombinant Antibody (MAb24B)
Brand: abinScience
SKU: VK658013
Price: 126 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

VK658013

Description

Anti-HPV16 Minor capsid protein L2 Recombinant Antibody (MAb24B) (VK658013) is a human monoclonal antibody detecting Minor capsid protein L2 in WB. Suitable for Human papillomavirus 16 (HPV16), Human papillomavirus 18 (HPV18), Human papillomavirus 31 (HPV31), Human papillomavirus 33 (HPV33), Human papillomavirus 35 (HPV35), Human papillomavirus 51 (HPV51), Human papillomavirus 52 (HPV52), Human papillomavirus 58 (HPV58).

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human papillomavirus 16 (HPV16), Human papillomavirus 18 (HPV18), Human papillomavirus 31 (HPV31), Human papillomavirus 33 (HPV33), Human papillomavirus 35 (HPV35), Human papillomavirus 51 (HPV51), Human papillomavirus 52 (HPV52), Human papillomavirus 58 (HPV58)

Applications

Host species

Human

Clonality

Monoclonal

Isotype

IgG1, kappa

Clone ID

MAb24B

Target

Minor capsid protein L2, L2

Endotoxin level

< 10 EU/mg as determined by LAL method.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03107

Form

Liquid

Storage buffer

0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Minor capsid protein L2 is a ~50 kDa protein. Minor protein of the capsid that localizes along the inner surface of the virion, within the central cavities beneath the L1 pentamers. Plays a role in capsid stabilization through interaction with the major capsid protein L1. Once the virion enters the host cell, L2 escorts the genomic DNA into the nucleus by promoting escape from the endosomal compartments and traffic through the host Golgi network. Mechanistically, the C-terminus of L2 possesses a cell-penetrating peptide that protudes from the host endosome, interacts with host cytoplasmic retromer cargo and thereby mediates the capsid delivery to the host trans-Golgi network. Plays a role through its interaction with host dynein in the intracellular microtubule-dependent transport of viral capsid toward the nucleus.

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-HPV16 L2/Minor capsid protein L2 Antibody (MAb24B).
Bioactivity

Detects Human papillomavirus type 16 L2/Minor capsid protein L2 in indirect ELISAs.

References

Datasheet

Anti-HPV16 Minor capsid protein L2 Recombinant Antibody (MAb24B).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-HPV16 Minor capsid protein L2 Recombinant Antibody (MAb24B) (VK658013)

Overview

Images

References

Datasheet

SDS