Anti-HPV18 E7/Protein E7 Polyclonal Antibody (VK556024)

Name: Anti-HPV18 E7/Protein E7 Polyclonal Antibody
Brand: abinScience
SKU: VK556024
Price: 168 USD
Availability: InStock

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Prix(USD) :

Spécification :

50ug
100ug

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

VK556024

Description

Anti-HPV18 E7/Protein E7 Polyclonal Antibody (VK556024) is a rabbit polyclonal antibody detecting Protein E7 in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Reactivité des espèces

Human papillomavirus 18 (HPV18)

Applications

ELISA, IHC, WB

Espèce hôte

Rabbit

Clonalité

Polyclonal

Isotype

IgG

Immunogène

E. coli - derived recombinant HPV18 E7/Protein E7 (Met1-Gln105).

Applications testées

Cible

Protein E7, E7

Niveau d'endotoxines

Please contact with the lab for this information.

Purification

Purified by antigen affinity column.

Numéro d'accès

P06788

Forme

Liquid

Tampon de stockage

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Protein E7 is a ~11 kDa protein. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation.

1. Lau, L. et al. (2015) Science (New York, N.Y.) 350, 568-71. PMID: 26405230

Note

For research use only

Images

Western blot

Western blot analysis was performed using anti-E7 protein polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant HPV18 E7 (Catalog No: VK556062)

Reférences

Fiche technique