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| カタログ番号 | VK556024 | ||||||||
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| 説明 |
Anti-HPV18 E7/Protein E7 Polyclonal Antibody (VK556024) is a rabbit polyclonal antibody detecting Protein E7 in ELISA, IHC, WB.
Highlights
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| 種反応性 | Human papillomavirus 18 (HPV18) | ||||||||
| アプリケーション | ELISA, IHC, WB | ||||||||
| 宿主種 | Rabbit | ||||||||
| クローン性 | Polyclonal | ||||||||
| アイソタイプ | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant HPV18 E7/Protein E7 (Met1-Gln105). | ||||||||
| テスト済みアプリケーション | WB | ||||||||
| ターゲット | Protein E7, E7 | ||||||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||||||
| 精製 | Purified by antigen affinity column. | ||||||||
| アクセッション番号 | P06788 | ||||||||
| 形態 | Liquid | ||||||||
| 保存バッファー | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 背景 | Protein E7 is a ~11 kDa protein. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication. E7 protein has both transforming and trans-activating activities. Induces the disassembly of the E2F1 transcription factor from RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Interferes with host histone deacetylation mediated by HDAC1 and HDAC2, leading to transcription activation. 1. Lau, L. et al. (2015) Science (New York, N.Y.) 350, 568-71. PMID: 26405230 | ||||||||
| 注意事項 | For research use only |
Western blot analysis was performed using anti-E7 protein polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant HPV18 E7 (Catalog No: VK556062)
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中国武漢市深敦寺路666号C棟、武漢、430206
