Anti-Human ABCB11 Recombinant Antibody (SAA1534) (HF994013)

Name: Anti-Human ABCB11 Recombinant Antibody (SAA1534)
Brand: abinScience
SKU: HF994013
Price: 196 USD
Availability: InStock

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Prix(USD) :

Spécification :

50ug
100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HF994013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1534

Cible

BSEP, Bile salt export pump, ABCB11, ATP-binding cassette sub-family B member 11

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

O95342

RRID

Anti-Human ABCB11 Antibody (SAA1534) (abinScience Cat# HF994013, RRID:AB_3727295)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Bile salt export pump (ABCB11) is a ~146 kDa protein. Catalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates in hepatic bile acid homeostasis and consequently to lipid homeostasis through regulation of biliary lipid secretion in a bile salts dependent manner. Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts. Also transports non-bile acid compounds, such as pravastatin and fexofenadine in an ATP-dependent manner and may be involved in their biliary excretion.

1. Hayashi, H. et al. (2005) Hepatology (Baltimore, Md.) 41, 916-24. PMID: 15791618

2. Hayashi, H. et al. (2005) Biochimica et biophysica acta 1738, 54-62. PMID: 16332456

3. Yabuuchi, H. et al. (2008) Biopharmaceutics & drug disposition 29, 441-8. PMID: 18985798

4. Paulusma, CC. et al. (2009) The Journal of biological chemistry 284, 9947-54. PMID: 19228692

5. Ho, RH. et al. (2010) Pharmacogenetics and genomics 20, 45-57. PMID: 20010382

6. Kato, T. et al. (2010) Biochimica et biophysica acta 1801, 1005-12. PMID: 20398791

7. Hayashi, H. et al. (2012) Hepatology (Baltimore, Md.) 55, 1889-900. PMID: 22262466

8. Guyot, C. et al. (2014) Molecular pharmacology 85, 909-20. PMID: 24711118

9. Imagawa, K. et al. (2018) Journal of human genetics 63, 569-577. PMID: 29507376

10. Wang, L. et al. (2020) Cell research 30, 623-625. PMID: 32203132

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human ABCB11 Antibody (SAA1534)

Reférences

Fiche technique

Anti-Human ABCB11 Recombinant Antibody (SAA1534).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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