Anti-Human ABCB11 Recombinant Antibody (SAA1534) (HF994013)

Name: Anti-Human ABCB11 Recombinant Antibody (SAA1534)
Brand: abinScience
SKU: HF994013
Price: 196 USD
Availability: InStock

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Спецификация:

50ug
100ug
1mg

Количество:

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Обзор
Изображения
Ссылки
Даташит
SDS

Обзор

Каталожный номер

HF994013

Реактивность видов

Human

Применения

ELISA

Хозяинский вид

Mouse

Клоональность

Monoclonal

Изотип

IgG2a, kappa

ID клона

SAA1534

Цель

BSEP, Bile salt export pump, ABCB11, ATP-binding cassette sub-family B member 11

Уровень эндотоксинов

Please contact with the lab for this information.

Чистота

>95% as determined by SDS-PAGE.

Очистка

Protein A/G purified from cell culture supernatant.

Номер доступа

O95342

RRID

Anti-Human ABCB11 Antibody (SAA1534) (abinScience Cat# HF994013, RRID:AB_3727295)

Форма

Liquid

Буфер хранения

0.01M PBS pH 7.4

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:2000-1:20000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Фон

Bile salt export pump (ABCB11) is a ~146 kDa protein. Catalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates in hepatic bile acid homeostasis and consequently to lipid homeostasis through regulation of biliary lipid secretion in a bile salts dependent manner. Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts. Also transports non-bile acid compounds, such as pravastatin and fexofenadine in an ATP-dependent manner and may be involved in their biliary excretion.

1. Hayashi, H. et al. (2005) Hepatology (Baltimore, Md.) 41, 916-24. PMID: 15791618

2. Hayashi, H. et al. (2005) Biochimica et biophysica acta 1738, 54-62. PMID: 16332456

3. Yabuuchi, H. et al. (2008) Biopharmaceutics & drug disposition 29, 441-8. PMID: 18985798

4. Paulusma, CC. et al. (2009) The Journal of biological chemistry 284, 9947-54. PMID: 19228692

5. Ho, RH. et al. (2010) Pharmacogenetics and genomics 20, 45-57. PMID: 20010382

6. Kato, T. et al. (2010) Biochimica et biophysica acta 1801, 1005-12. PMID: 20398791

7. Hayashi, H. et al. (2012) Hepatology (Baltimore, Md.) 55, 1889-900. PMID: 22262466

8. Guyot, C. et al. (2014) Molecular pharmacology 85, 909-20. PMID: 24711118

9. Imagawa, K. et al. (2018) Journal of human genetics 63, 569-577. PMID: 29507376

10. Wang, L. et al. (2020) Cell research 30, 623-625. PMID: 32203132

Примечание

For research use only.

Изображения

SDS-PAGE

SDS-PAGE for Anti-Human ABCB11 Antibody (SAA1534)

Ссылки

Даташит

Anti-Human ABCB11 Recombinant Antibody (SAA1534).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа