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Anti-Human ABCC1 Recombinant Antibody (SAA1629) (HW501013)

Anti-Human ABCC1 Recombinant Antibody (SAA1629)
Anti-Human ABCC1 Recombinant Antibody (SAA1629)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
  • 1mg
Número:
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  • SDS

Vista general
Número de catálogoHW501013
Reactividad de especiesHuman
AplicacionesELISA
Especie huéspedMouse
ClonalidadMonoclonal
IsotipoIgG2a, kappa
ID de clonSAA1629
Objetivo Leukotriene C(4) transporter, ABCC1, MRP, Multidrug resistance-associated protein 1, MRP1, Glutathione-S-conjugate-translocating ATPase ABCC1, LTC4 transporter, ATP-binding cassette sub-family C member 1
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >95% as determined by SDS-PAGE.
Purificación Protein A/G purified from cell culture supernatant.
Número de acceso P33527
RRID Anti-Human ABCC1 Antibody (SAA1629) (abinScience Cat# HW501013, RRID:AB_3727390)
Forma Liquid
Buffer de almacenamiento 0.01M PBS pH 7.4

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto
Aplicación Dilución
ELISA 1:2000-1:20000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo

Multidrug resistance-associated protein 1 (ABCC1) is a ~171 kDa protein. Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation.

1. Sjölinder, M. et al. (1999) Journal of lipid research 40, 439-46. PMID: 10064732
2. Robbiani, DF. et al. (2000) Cell 103, 757-68. PMID: 11114332
3. Conseil, G. et al. (2006) The Journal of biological chemistry 281, 43-50. PMID: 16230346
4. Leier, I. et al. (1994) The Journal of biological chemistry 269, 27807-10. PMID: 7961706
5. Stride, BD. et al. (1997) Molecular pharmacology 52, 344-53. PMID: 9281595
Nota For research use only.
Imágenes
  • Anti-Human ABCC1 Recombinant Antibody (SAA1629)

    SDS-PAGE

    SDS-PAGE for Anti-Human ABCC1 Antibody (SAA1629)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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