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| カタログ番号 | HW501013 | ||||
|---|---|---|---|---|---|
| 種反応性 | Human | ||||
| アプリケーション | ELISA | ||||
| 宿主種 | Mouse | ||||
| クローン性 | Monoclonal | ||||
| アイソタイプ | IgG2a, kappa | ||||
| クローンID | SAA1629 | ||||
| ターゲット | Leukotriene C(4) transporter, ABCC1, MRP, Multidrug resistance-associated protein 1, MRP1, Glutathione-S-conjugate-translocating ATPase ABCC1, LTC4 transporter, ATP-binding cassette sub-family C member 1 | ||||
| エンドトキシンレベル | Please contact with the lab for this information. | ||||
| 純度 | >95% as determined by SDS-PAGE. | ||||
| 精製 | Protein A/G purified from cell culture supernatant. | ||||
| アクセッション番号 | P33527 | ||||
| RRID | Anti-Human ABCC1 Antibody (SAA1629) (abinScience Cat# HW501013, RRID:AB_3727390) |
||||
| 形態 | Liquid | ||||
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
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| 製品使用情報 |
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| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 背景 | Multidrug resistance-associated protein 1 (ABCC1) is a ~171 kDa protein. Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs by decreasing accumulation of drug in cells, and by mediating ATP- and GSH-dependent drug export. Hydrolyzes ATP with low efficiency. Catalyzes the export of sphingosine 1-phosphate from mast cells independently of their degranulation. 1. Sjölinder, M. et al. (1999) Journal of lipid research 40, 439-46. PMID: 10064732 2. Robbiani, DF. et al. (2000) Cell 103, 757-68. PMID: 11114332 3. Conseil, G. et al. (2006) The Journal of biological chemistry 281, 43-50. PMID: 16230346 4. Leier, I. et al. (1994) The Journal of biological chemistry 269, 27807-10. PMID: 7961706 5. Stride, BD. et al. (1997) Molecular pharmacology 52, 344-53. PMID: 9281595 | ||||
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human ABCC1 Antibody (SAA1629)
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