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Anti-Human ABCC2 Polyclonal Antibody (HV352014)

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Vista general
Número de catálogoHV352014
Descripción
Anti-Human ABCC2 Polyclonal Antibody (HV352014) is a rabbit polyclonal antibody detecting ABCC2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant Human ABCC2 (Ile1300-Glu1534).
Objetivo ATP-binding cassette sub-family C member 2, Multidrug resistance-associated protein 2, Canalicular multispecific organic anion transporter 1, ABCC2, CMOAT, Canalicular multidrug resistance protein, MRP2, CMRP, CMOAT1
Purificación Purified by antigen affinity column.
Número de acceso Q92887
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

ATP-binding cassette sub-family C member 2 (ABCC2) is a ~174 kDa protein. ATP-dependent transporter of the ATP-binding cassette (ABC) family that binds and hydrolyzes ATP to enable active transport of various substrates including many drugs, toxicants and endogenous compound across cell membranes. Transports a wide variety of conjugated organic anions such as sulfate-, glucuronide- and glutathione (GSH)-conjugates of endo- and xenobiotics substrates. Mediates hepatobiliary excretion of mono- and bis-glucuronidated bilirubin molecules and therefore play an important role in bilirubin detoxification. Also mediates hepatobiliary excretion of others glucuronide conjugates such as 17beta-estradiol 17-glucosiduronic acid and leukotriene C4. Transports sulfated bile salt such as taurolithocholate sulfate.

1. Cui, Y. et al. (1999) Molecular pharmacology 55, 929-37. PMID: 10220572
2. Kamisako, T. et al. (1999) Hepatology (Baltimore, Md.) 30, 485-90. PMID: 10421658
3. Ito, K. et al. (2001) The Journal of biological chemistry 276, 38108-14. PMID: 11500505
4. Hayashi, H. et al. (2005) Biochimica et biophysica acta 1738, 54-62. PMID: 16332456
5. Huisman, MT. et al. (2002) AIDS (London, England) 16, 2295-301. PMID: 12441801
Nota For research use only.
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Referencias
Datasheet
Download SDS PDF
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human ABCC2 Polyclonal Antibody

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