Anti-Human ABCC2 Polyclonal Antibody (HV352014)

Name: Anti-Human ABCC2 Polyclonal Antibody
Brand: abinScience
SKU: HV352014
Price: 168 USD
Availability: InStock

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Каталожный номер

HV352014

Описание

Anti-Human ABCC2 Polyclonal Antibody (HV352014) is a rabbit polyclonal antibody detecting ABCC2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Реактивность видов

Human

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human ABCC2 (Ile1300-Glu1534).

Цель

ATP-binding cassette sub-family C member 2, Multidrug resistance-associated protein 2, Canalicular multispecific organic anion transporter 1, ABCC2, CMOAT, Canalicular multidrug resistance protein, MRP2, CMRP, CMOAT1

Очистка

Purified by antigen affinity column.

Номер доступа

Q92887

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

ATP-binding cassette sub-family C member 2 (ABCC2) is a ~174 kDa protein. ATP-dependent transporter of the ATP-binding cassette (ABC) family that binds and hydrolyzes ATP to enable active transport of various substrates including many drugs, toxicants and endogenous compound across cell membranes. Transports a wide variety of conjugated organic anions such as sulfate-, glucuronide- and glutathione (GSH)-conjugates of endo- and xenobiotics substrates. Mediates hepatobiliary excretion of mono- and bis-glucuronidated bilirubin molecules and therefore play an important role in bilirubin detoxification. Also mediates hepatobiliary excretion of others glucuronide conjugates such as 17beta-estradiol 17-glucosiduronic acid and leukotriene C4. Transports sulfated bile salt such as taurolithocholate sulfate.

1. Cui, Y. et al. (1999) Molecular pharmacology 55, 929-37. PMID: 10220572

2. Kamisako, T. et al. (1999) Hepatology (Baltimore, Md.) 30, 485-90. PMID: 10421658

3. Ito, K. et al. (2001) The Journal of biological chemistry 276, 38108-14. PMID: 11500505

4. Hayashi, H. et al. (2005) Biochimica et biophysica acta 1738, 54-62. PMID: 16332456

5. Huisman, MT. et al. (2002) AIDS (London, England) 16, 2295-301. PMID: 12441801

Примечание

For research use only.

Изображения

Ссылки

Даташит

Anti-Human ABCC2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Рекомбинантные Белки

Антитела

Наборы для анализа

Anti-Human ABCC2 Polyclonal Antibody (HV352014)

Обзор

Изображения

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