Anti-Human ACVR1C Recombinant Antibody (SAA1706) (HV040013)

Name: Anti-Human ACVR1C Recombinant Antibody (SAA1706)
Brand: abinScience
SKU: HV040013
Price: 196 USD
Availability: InStock

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Spécification :

50ug
100ug
1mg

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HV040013

Reactivité des espèces

Human

Applications

ELISA

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1706

Cible

Activin receptor-like kinase 7, ALK7, ACVR1C, Activin receptor type IC, ALK-7, Activin receptor type-1C, ACTR-IC

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

Q8NER5

RRID

Anti-Human ACVR1C Antibody (SAA1706) (abinScience Cat# HV040013, RRID:AB_3727467)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Activin receptor type-1C (ACVR1C) is a ~54 kDa protein. Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consists of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B, activin E and NODAL. Upon NODAL binding, activation results in increased apoptosis and reduced proliferation through suppression of AKT signaling and the activation of Smad2-dependent signaling pathway in pancreatic beta-cells, trophoblasts, epithelial or neuronal cells.

1. Xu, G. et al. (2004) The Journal of clinical endocrinology and metabolism 89, 5523-34. PMID: 15531507

2. Munir, S. et al. (2004) The Journal of biological chemistry 279, 31277-86. PMID: 15150278

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human ACVR1C Antibody (SAA1706)

Reférences

Fiche technique

Anti-Human ACVR1C Recombinant Antibody (SAA1706).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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