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| カタログ番号 | HV188025 |
|---|---|
| 説明 |
Anti-Human ADAMTS1 Monoclonal Antibody (1A695) [1A695] (HV188025) is a mouse monoclonal antibody detecting ADAMTS1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 種反応性 | Human |
| アプリケーション | ELISA, IHC, WB |
| 宿主種 | Mouse |
| クローン性 | Monoclonal |
| アイソタイプ | IgG |
| クローンID | 1A695 |
| 免疫原 | E. coli - derived recombinant human ADAMTS1 (Arg258-Pro467). |
| ターゲット | A disintegrin and metalloproteinase with thrombospondin motifs 1, ADAM-TS 1, ADAM-TS1, ADAMTS-1, EC:3.4.24.-, METH-1, ADAMTS1 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | Q9UHI8 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1) is a ~105 kDa protein. Metalloprotease which cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. Also cleaves COMP. Has angiogenic inhibitor activity. May play a critical role in follicular rupture. 1. de Groot, R. et al. (2025) Matrix biology : journal of the International Society for Matrix Biology 135, 106-124. PMID: 39672391 2. Vázquez, F. et al. (1999) The Journal of biological chemistry 274, 23349-57. PMID: 10438512 |
| 注意事項 | For research use only. |
SDS-PAGE for Anti-Human ADAMTS1 Monoclonal Antibody (1A695)
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