Anti-Human ADAMTS1 Monoclonal Antibody (1A694) (HV188015)

Name: Anti-Human ADAMTS1 Monoclonal Antibody (1A694)
Brand: abinScience
SKU: HV188015
Price: 106 USD
Availability: InStock

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Overview

Catalog No.	HV188015
Description	Anti-Human ADAMTS1 Monoclonal Antibody (1A694) [1A694] (HV188015) is a mouse monoclonal antibody detecting ADAMTS1 in ELISA, IHC, WB. Suitable for Human. Highlights ●Recombinant — Superior batch-to-batch reproducibility with defined sequences. ●Multi-Application — Validated across multiple applications.
Species reactivity	Human
Applications	ELISA, IHC, WB
Host species	Mouse
Isotype	IgG
Clone ID	1A694
Clonality	Monoclonal
Immunogen	E. coli - derived recombinant human ADAMTS1 (Arg258-Pro467).
Target	A disintegrin and metalloproteinase with thrombospondin motifs 1, ADAM-TS 1, ADAM-TS1, ADAMTS-1, EC:3.4.24.-, METH-1, ADAMTS1
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9UHI8
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background	A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1) is a ~105 kDa protein. Metalloprotease which cleaves aggrecan, a cartilage proteoglycan, at the '1938-Glu-\|-Leu-1939' site (within the chondroitin sulfate attachment domain), and may be involved in its turnover. Also cleaves COMP. Has angiogenic inhibitor activity. May play a critical role in follicular rupture. 1. de Groot, R. et al. (2025) Matrix biology : journal of the International Society for Matrix Biology 135, 106-124. PMID: 39672391 2. Vázquez, F. et al. (1999) The Journal of biological chemistry 274, 23349-57. PMID: 10438512
Note	For research use only.