Anti-Human ADRB1 Recombinant Antibody (6B9), APC (HY486137)

Name: Anti-Human ADRB1 Recombinant Antibody (6B9), APC
Brand: abinScience
SKU: HY486137
Price: 290 USD
Availability: InStock

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Vista general

Número de catálogo	HY486137
Reactividad de especies	Human
Aplicaciones	ELISA, FCM
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	VHH-hFc
ID de clon	6B9
Conjugación	APC
Objetivo	Beta-1 adrenoreceptor, ADRB1, Beta-1 adrenergic receptor, ADRB1R, B1AR, Beta-1 adrenoceptor
Nivel de endotoxinas	Please contact with the lab for this information.
Productos asociados	VHH-hFc (IgG1) Isotype Control antibody (cAb-Lys2), APC
Número de acceso	P08588
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Store at 4°C for 12 months. Protect from light. Do not freeze.
Fondo	Beta-1 adrenergic receptor (ADRB1) is a ~51 kDa protein. G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction. Also delivers proapoptotic signals in cardiomyocytes. 1. Mason, DA. et al. (1999) The Journal of biological chemistry 274, 12670-4. PMID: 10212248 2. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161 3. He, J. et al. (2004) The Journal of biological chemistry 279, 50190-6. PMID: 15358775 4. Xu, X. et al. (2021) Cell research 31, 569-579. PMID: 33093660 5. Börjesson, M. et al. (2000) European heart journal 21, 1853-8. PMID: 11052857 6. Ranade, K. et al. (2002) American journal of human genetics 70, 935-42. PMID: 11854867 7. Shi, G. et al. (2019) Neuron 103, 1044-1055.e7. PMID: 31473062
Nota	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human ADRB1 Recombinant Antibody (6B9), APC.pdf

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