Anti-Human ADRB1 Recombinant Antibody (6B9) (HY486107)

Name: Anti-Human ADRB1 Recombinant Antibody (6B9)
Brand: abinScience
SKU: HY486107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	HY486107
Species reactivity	Human
Applications	ELISA, FCM
Host species	Human
Isotype	VHH-hFc
Clone ID	6B9
Clonality	Monoclonal
Target	Beta-1 adrenoreceptor, ADRB1, Beta-1 adrenergic receptor, ADRB1R, B1AR, Beta-1 adrenoceptor
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P08588
Form	Liquid
Storage buffer	9mM Citric acid monohydrate, 41mM Na2HPO4, 1% Mannitol, 5% Trehalose, 0.02% Tween 20, pH 6.5. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Beta-1 adrenergic receptor (ADRB1) is a ~51 kDa protein. G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction. Also delivers proapoptotic signals in cardiomyocytes. 1. Mason, DA. et al. (1999) The Journal of biological chemistry 274, 12670-4. PMID: 10212248 2. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161 3. He, J. et al. (2004) The Journal of biological chemistry 279, 50190-6. PMID: 15358775 4. Xu, X. et al. (2021) Cell research 31, 569-579. PMID: 33093660 5. Börjesson, M. et al. (2000) European heart journal 21, 1853-8. PMID: 11052857 6. Ranade, K. et al. (2002) American journal of human genetics 70, 935-42. PMID: 11854867 7. Shi, G. et al. (2019) Neuron 103, 1044-1055.e7. PMID: 31473062
Note	For research use only.

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SDS-PAGE for Anti-Human ADRB1 Antibody (6B9)

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Datasheet

Anti-Human ADRB1 Recombinant Antibody (6B9).pdf

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Anti-Human ADRB1 Recombinant Antibody (6B9) (HY486107)

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