Anti-Human ADRB1 Recombinant Antibody (6B9), APC (HY486137)

Name: Anti-Human ADRB1 Recombinant Antibody (6B9), APC
Brand: abinScience
SKU: HY486137
Price: 290 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HY486137
Reactivité des espèces	Human
Applications	ELISA, FCM
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	VHH-hFc
ID de clone	6B9
Conjugaison	APC
Cible	Beta-1 adrenoreceptor, ADRB1, Beta-1 adrenergic receptor, ADRB1R, B1AR, Beta-1 adrenoceptor
Niveau d'endotoxines	Please contact with the lab for this information.
Produits associés	VHH-hFc (IgG1) Isotype Control antibody (cAb-Lys2), APC
Numéro d'accès	P08588
Forme	Liquid
Tampon de stockage	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Contexte	Beta-1 adrenergic receptor (ADRB1) is a ~51 kDa protein. G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction. Also delivers proapoptotic signals in cardiomyocytes. 1. Mason, DA. et al. (1999) The Journal of biological chemistry 274, 12670-4. PMID: 10212248 2. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161 3. He, J. et al. (2004) The Journal of biological chemistry 279, 50190-6. PMID: 15358775 4. Xu, X. et al. (2021) Cell research 31, 569-579. PMID: 33093660 5. Börjesson, M. et al. (2000) European heart journal 21, 1853-8. PMID: 11052857 6. Ranade, K. et al. (2002) American journal of human genetics 70, 935-42. PMID: 11854867 7. Shi, G. et al. (2019) Neuron 103, 1044-1055.e7. PMID: 31473062
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Human ADRB1 Recombinant Antibody (6B9), APC.pdf

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