Anti-Human ADRB1 Recombinant Antibody (6B9), APC (HY486137)

Name: Anti-Human ADRB1 Recombinant Antibody (6B9), APC
Brand: abinScience
SKU: HY486137
Price: 290 USD
Availability: InStock

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概要

カタログ番号	HY486137
種反応性	Human
アプリケーション	ELISA, FCM
宿主種	Human
クローン性	Monoclonal
アイソタイプ	VHH-hFc
クローンID	6B9
抱合	APC
ターゲット	Beta-1 adrenoreceptor, ADRB1, Beta-1 adrenergic receptor, ADRB1R, B1AR, Beta-1 adrenoceptor
エンドトキシンレベル	Please contact with the lab for this information.
関連製品	VHH-hFc (IgG1) Isotype Control antibody (cAb-Lys2), APC
アクセッション番号	P08588
形態	Liquid
保存バッファー	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Store at 4°C for 12 months. Protect from light. Do not freeze.
背景	Beta-1 adrenergic receptor (ADRB1) is a ~51 kDa protein. G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction. Also delivers proapoptotic signals in cardiomyocytes. 1. Mason, DA. et al. (1999) The Journal of biological chemistry 274, 12670-4. PMID: 10212248 2. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161 3. He, J. et al. (2004) The Journal of biological chemistry 279, 50190-6. PMID: 15358775 4. Xu, X. et al. (2021) Cell research 31, 569-579. PMID: 33093660 5. Börjesson, M. et al. (2000) European heart journal 21, 1853-8. PMID: 11052857 6. Ranade, K. et al. (2002) American journal of human genetics 70, 935-42. PMID: 11854867 7. Shi, G. et al. (2019) Neuron 103, 1044-1055.e7. PMID: 31473062
注意事項	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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参考文献

データシート

Anti-Human ADRB1 Recombinant Antibody (6B9), APC.pdf

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Anti-Human ADRB1 Recombinant Antibody (6B9), APC (HY486137)

概要

イメージ

参考文献

データシート

SDS

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