

| Numéro de catalogue | HP067014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human AEBP2 Polyclonal Antibody (HP067014) is a rabbit polyclonal antibody detecting AEBP2 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human AEBP2 (Ser274-Ser358). | ||||||||
| Cible | Adipocyte enhancer-binding protein 2, Zinc finger protein AEBP2, AEBP2, AE-binding protein 2 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | Q6ZN18 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Contexte | Zinc finger protein AEBP2 is a ~54 kDa protein. Acts as an accessory subunit for the core Polycomb repressive complex 2 (PRC2), which mediates histone H3K27 (H3K27me3) trimethylation on chromatin leading to transcriptional repression of the affected target gene. Plays a role in nucleosome localization of the PRC2 complex. 1. Cao, R. et al. (2004) Molecular cell 15, 57-67. PMID: 15225548 2. Chen, S. et al. (2018) Molecular cell 69, 840-852.e5. PMID: 29499137 3. Chen, S. et al. (2020) Molecular cell 77, 1265-1278.e7. PMID: 31959557 | ||||||||
| Note | For research use only. |
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