Human AEBP2 Recombinant Protein (N-GST & C-His) (HP067022)

Name: Human AEBP2 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HP067022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HP067022
Description	Recombinant Human AEBP2 Protein, N-GST & C-His (HP067022) expressed in E. coli, spanning Ser274-Ser358. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q6ZN18
Protein length	Ser274-Ser358
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	37.43 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	AE-binding protein 2, AEBP2, Adipocyte enhancer-binding protein 2, Zinc finger protein AEBP2
Background	Zinc finger protein AEBP2 is a ~54 kDa protein. Acts as an accessory subunit for the core Polycomb repressive complex 2 (PRC2), which mediates histone H3K27 (H3K27me3) trimethylation on chromatin leading to transcriptional repression of the affected target gene. Plays a role in nucleosome localization of the PRC2 complex. 1. Cao, R. et al. (2004) Molecular cell 15, 57-67. PMID: 15225548 2. Chen, S. et al. (2018) Molecular cell 69, 840-852.e5. PMID: 29499137 3. Chen, S. et al. (2020) Molecular cell 77, 1265-1278.e7. PMID: 31959557
Note	For research use only

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Datasheet

Human AEBP2 Recombinant Protein (N-GST & C-His).pdf

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Human AEBP2 Recombinant Protein (N-GST & C-His) (HP067022)

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