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Anti-Human AEBP2 Polyclonal Antibody (HP067014)

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Overview
Catalog No.HP067014
Species reactivityHuman, Mouse
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human AEBP2 (Ser274-Ser358).
Target Adipocyte enhancer-binding protein 2, Zinc finger protein AEBP2, AEBP2, AE-binding protein 2
Purification Purified by antigen affinity column.
Accession Q6ZN18
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Zinc finger protein AEBP2 is a ~54 kDa protein. Acts as an accessory subunit for the core Polycomb repressive complex 2 (PRC2), which mediates histone H3K27 (H3K27me3) trimethylation on chromatin leading to transcriptional repression of the affected target gene. Plays a role in nucleosome localization of the PRC2 complex.

1. Cao, R. et al. (2004) Molecular cell 15, 57-67. PMID: 15225548
2. Chen, S. et al. (2018) Molecular cell 69, 840-852.e5. PMID: 29499137
3. Chen, S. et al. (2020) Molecular cell 77, 1265-1278.e7. PMID: 31959557
Note For research use only.
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Formula
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Anti-Human AEBP2 Polyclonal Antibody

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