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Anti-Human APOBEC3H Polyclonal Antibody (HB477014)

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Vista general
Número de catálogoHB477014
Descripción
Anti-Human APOBEC3H Polyclonal Antibody (HB477014) is a rabbit polyclonal antibody detecting DNA dC->dU-editing enzyme APOBEC-3H; 3.5.4.38; APOBEC-related protein 10; ARP-10; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H; A3H; APOBEC3H in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
Reactividad de especiesHuman
AplicacionesELISA, IHC, WB
Especie huéspedRabbit
ClonalidadPolyclonal
IsotipoIgG
Inmunógeno E. coli - derived recombinant human APOBEC3H (Met1-Val200).
Objetivo DNA dC->dU-editing enzyme APOBEC-3H; 3.5.4.38; APOBEC-related protein 10; ARP-10; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3H; A3H; APOBEC3H
Nivel de endotoxinas Please contact with the lab for this information.
Purificación Purified by antigen affinity column.
Número de acceso Q6NTF7
Forma Liquid
Buffer de almacenamiento 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Información de uso del producto
Aplicación Dilución
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo

DNA dC->dU-editing enzyme APOBEC-3H (APOBEC3H) is a ~23 kDa protein. DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. The A3H-var/haplotype 2 exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single- or double-stranded RNA.

1. OhAinle, M. et al. (2006) Journal of virology 80, 3853-62. PMID: 16571802
2. Dang, Y. et al. (2006) Journal of virology 80, 10522-33. PMID: 16920826
3. OhAinle, M. et al. (2008) Cell host & microbe 4, 249-59. PMID: 18779051
4. Tan, L. et al. (2009) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23, 279-87. PMID: 18827027
5. Stenglein, MD. et al. (2010) Nature structural & molecular biology 17, 222-9. PMID: 20062055
6. Phalora, PK. et al. (2012) Journal of virology 86, 11712-24. PMID: 22915799
7. Shaban, NM. et al. (2018) Molecular cell 69, 75-86.e9. PMID: 29290613
8. Dang, Y. et al. (2008) The Journal of biological chemistry 283, 11606-14. PMID: 18299330
9. Hultquist, JF. et al. (2011) Journal of virology 85, 11220-34. PMID: 21835787
10. Chaipan, C. et al. (2013) Journal of virology 87, 444-53. PMID: 23097438
Nota For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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