Anti-Human AQP4/Aquaporin-4 Recombinant Antibody (SAA1755) (HX181013)

Name: Anti-Human AQP4/Aquaporin-4 Recombinant Antibody (SAA1755)
Brand: abinScience
SKU: HX181013
Price: 110 USD
Availability: InStock

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Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HX181013

Reactivité des espèces

Human

Applications

ELISA, FCM, IF

Espèce hôte

Mouse

Clonalité

Monoclonal

Isotype

IgG2a, kappa

ID de clone

SAA1755

Cible

WCH4, Aquaporin-4, Mercurial-insensitive water channel, AQP-4, MIWC, AQP4

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P55087

RRID

Anti-Human AQP4/Aquaporin-4 Antibody (SAA1755) (abinScience Cat# HX181013, RRID:AB_3727516)

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Contexte

Aquaporin-4 (AQP4) is a ~34 kDa protein. Forms a water-specific channel. Plays an important role in brain water homeostasis. It is involved in glymphatic solute transport and is required for a normal rate of water exchange across the blood brain interface. Required for normal levels of cerebrospinal fluid influx into the brain cortex and parenchyma along paravascular spaces that surround penetrating arteries, and for normal drainage of interstitial fluid along paravenous drainage pathways. Thereby, it is required for normal clearance of solutes from the brain interstitial fluid, including soluble beta-amyloid peptides derived from APP.

1. Ho, JD. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 7437-42. PMID: 19383790

2. Yang, B. et al. (1995) The Journal of biological chemistry 270, 22907-13. PMID: 7559426

3. Misaka, T. et al. (1996) FEBS letters 381, 208-12. PMID: 8601457

4. Passchier, EMJ. et al. (2023) Brain : a journal of neurology 146, 3444-3454. PMID: 37143309

Note

For research use only.

Isotype Control

Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023)

Images

SDS-PAGE

SDS-PAGE for Anti-Human AQP4/Aquaporin-4 Antibody (SAA1755).

Reférences

Fiche technique

Anti-Human AQP4/Aquaporin-4 Recombinant Antibody (SAA1755).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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