

| Numéro de catalogue | HD512014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human ARL1 Polyclonal Antibody (HD512014) is a rabbit polyclonal antibody detecting ARL1. Suitable for Rat, Human, and Mouse.
Highlights
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| Reactivité des espèces | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Espèce hôte | Rabbit | ||||||||
| Clonalité | Polyclonal | ||||||||
| Isotype | IgG | ||||||||
| Immunogène | E. coli - derived recombinant Human ARL1 (Met1-Gln181). | ||||||||
| Cible | ADP-ribosylation factor-like protein 1, ARL1 | ||||||||
| Niveau d'endotoxines | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Numéro d'accès | P40616 | ||||||||
| Forme | Liquid | ||||||||
| Tampon de stockage | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
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| Informations d'utilisation du produit |
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| Contexte | ADP-ribosylation factor-like protein 1 (ARL1) is a ~20 kDa protein. GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. 1. Man, Z. et al. (2011) The Journal of biological chemistry 286, 11569-78. PMID: 21239483 2. Nakamura, K. et al. (2012) The Journal of biological chemistry 287, 25478-89. PMID: 22679020 3. Galindo, A. et al. (2016) Cell reports 16, 839-50. PMID: 27373159 4. Wang, R. et al. (2016) Journal of molecular cell biology 8, 459-461. PMID: 27436755 5. Hong, JX. et al. (1998) The Journal of biological chemistry 273, 15872-6. PMID: 9624189 6. Lu, L. et al. (2003) Molecular biology of the cell 14, 3767-81. PMID: 12972563 7. Gehart, H. et al. (2012) Developmental cell 23, 756-68. PMID: 22981988 | ||||||||
| Note | For research use only |
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