

| Catalog No. | HD512012 |
|---|---|
| Description |
Recombinant Human ARL1 Protein, N-His (HD512012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Expression system | E. coli |
| Accession | P40616 |
| Protein length | Met1-Gln181 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | ADP-ribosylation factor-like protein 1, ARL1 |
| Background | ADP-ribosylation factor-like protein 1 is a ~20 kDa protein. GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. 1. Man, Z. et al. (2011) The Journal of biological chemistry 286, 11569-78. PMID: 21239483 2. Nakamura, K. et al. (2012) The Journal of biological chemistry 287, 25478-89. PMID: 22679020 3. Galindo, A. et al. (2016) Cell reports 16, 839-50. PMID: 27373159 4. Wang, R. et al. (2016) Journal of molecular cell biology 8, 459-461. PMID: 27436755 5. Hong, JX. et al. (1998) The Journal of biological chemistry 273, 15872-6. PMID: 9624189 6. Lu, L. et al. (2003) Molecular biology of the cell 14, 3767-81. PMID: 12972563 7. Gehart, H. et al. (2012) Developmental cell 23, 756-68. PMID: 22981988 |
| Note | For research use only |
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