

| Catalog No. | HD512014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-Human ARL1 Polyclonal Antibody (HD512014) is a rabbit polyclonal antibody detecting ARL1. Suitable for Rat, Human, and Mouse.
Highlights
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| Species reactivity | Human, Mouse, Rat | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human ARL1 (Met1-Gln181). | ||||||||
| Target | ADP-ribosylation factor-like protein 1, ARL1 | ||||||||
| Endotoxin level | Please contact with the lab for this information. | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P40616 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Background | ADP-ribosylation factor-like protein 1 (ARL1) is a ~20 kDa protein. GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. 1. Man, Z. et al. (2011) The Journal of biological chemistry 286, 11569-78. PMID: 21239483 2. Nakamura, K. et al. (2012) The Journal of biological chemistry 287, 25478-89. PMID: 22679020 3. Galindo, A. et al. (2016) Cell reports 16, 839-50. PMID: 27373159 4. Wang, R. et al. (2016) Journal of molecular cell biology 8, 459-461. PMID: 27436755 5. Hong, JX. et al. (1998) The Journal of biological chemistry 273, 15872-6. PMID: 9624189 6. Lu, L. et al. (2003) Molecular biology of the cell 14, 3767-81. PMID: 12972563 7. Gehart, H. et al. (2012) Developmental cell 23, 756-68. PMID: 22981988 | ||||||||
| Note | For research use only |
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