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Anti-Human ARL1 Polyclonal Antibody (HD512014)

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Overview
Catalog No.HD512014
Description
Anti-Human ARL1 Polyclonal Antibody (HD512014) is a rabbit polyclonal antibody detecting ARL1. Suitable for Rat, Human, and Mouse.
Highlights
  • Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human ARL1 (Met1-Gln181).
Target ADP-ribosylation factor-like protein 1, ARL1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession P40616
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

ADP-ribosylation factor-like protein 1 (ARL1) is a ~20 kDa protein. GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells.

1. Man, Z. et al. (2011) The Journal of biological chemistry 286, 11569-78. PMID: 21239483
2. Nakamura, K. et al. (2012) The Journal of biological chemistry 287, 25478-89. PMID: 22679020
3. Galindo, A. et al. (2016) Cell reports 16, 839-50. PMID: 27373159
4. Wang, R. et al. (2016) Journal of molecular cell biology 8, 459-461. PMID: 27436755
5. Hong, JX. et al. (1998) The Journal of biological chemistry 273, 15872-6. PMID: 9624189
6. Lu, L. et al. (2003) Molecular biology of the cell 14, 3767-81. PMID: 12972563
7. Gehart, H. et al. (2012) Developmental cell 23, 756-68. PMID: 22981988
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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