Anti-Human ARL3 Polyclonal Antibody (HW758014)

Name: Anti-Human ARL3 Polyclonal Antibody
Brand: abinScience
SKU: HW758014
Price: 96 USD
Availability: InStock

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Обзор

Каталожный номер

HW758014

Описание

Anti-Human ARL3 Polyclonal Antibody (HW758014) is a rabbit polyclonal antibody detecting ARL3 in ELISA, IHC, WB. Suitable for Bovine, Danio rerio, Human, Mouse, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Реактивность видов

Human, Mouse, Rat

Применения

ELISA, IHC, WB

Хозяинский вид

Rabbit

Клоональность

Polyclonal

Изотип

IgG

Иммуноген

E. coli - derived recombinant Human ARL3 (Met1-Lys182).

Цель

ARFL3, ADP-ribosylation factor-like protein 3, ARL3

Очистка

Purified by antigen affinity column.

Номер доступа

P36405

Форма

Liquid

Буфер хранения

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.

Информация об использовании продукта

Применение	Разбавление
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Устойчивость и хранение

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Фон

ADP-ribosylation factor-like protein 3 (ARL3) is a ~20 kDa protein. Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins to the cilium, including myristoylated NPHP3 and prenylated INPP5E. Targets NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium.

1. Zhou, C. et al. (2006) Molecular biology of the cell 17, 2476-87. PMID: 16525022

2. Veltel, S. et al. (2008) FEBS letters 582, 2501-7. PMID: 18588884

3. Wright, KJ. et al. (2011) Genes & development 25, 2347-60. PMID: 22085962

4. Alkanderi, S. et al. (2018) American journal of human genetics 103, 612-620. PMID: 30269812

Примечание

For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-ARL3 polyclonal antibody at 1μg/ml on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate

Ссылки

Даташит

Anti-Human ARL3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

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