

| Número de catálogo | HP433013 | ||||
|---|---|---|---|---|---|
| Descripción |
Anti-Human ARTN/Artemin Recombinant Antibody (A10) (HP433013) is a mouse monoclonal antibody detecting ARTN/Artemin in ELISA. Suitable for Human.
Highlights
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| Reactividad de especies | Human | ||||
| Aplicaciones | ELISA | ||||
| Especie huésped | Mouse | ||||
| Clonalidad | Monoclonal | ||||
| Isotipo | IgG2a, kappa | ||||
| ID de clon | A10 | ||||
| Objetivo | EVN, Artemin, Enovin, ARTN, Neublastin | ||||
| Nivel de endotoxinas | < 10 EU/mg | ||||
| Pureza | >95% as determined by SDS-PAGE. | ||||
| Purificación | Protein A/G purified from cell culture supernatant. | ||||
| Número de acceso | Q5T4W7 | ||||
| RRID | Anti-Human ARTN/Artemin Antibody (A10) (abinScience Cat# HP433013, RRID:AB_3727192) |
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| Forma | Liquid | ||||
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
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| Información de uso del producto |
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| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| Fondo | Artemin (ARTN) is a ~22 kDa protein. Growth factor that supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Acts by binding to its coreceptor, GFRA3, leading to autophosphorylation and activation of the RET receptor. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. 1. Masure, S. et al. (1999) European journal of biochemistry 266, 892-902. PMID: 10583383 2. Baloh, RH. et al. (1998) Neuron 21, 1291-302. PMID: 9883723 3. Li, J. et al. (2019) eLife 8. PMID: 31535977 | ||||
| Nota | For research use only. | ||||
| Isotype Control | Mouse IgG2a (Fc Silence) Recombinant Isotype Control (MOPC 173) (MF533023) |

SDS-PAGE for Anti-Human ARTN/Artemin Antibody (A10)
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