Human ARTN/Artemin Recombinant Protein (N-His) (HP433012)

Name: Human ARTN/Artemin Recombinant Protein (N-His)
Brand: abinScience
SKU: HP433012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HP433012
Description	Recombinant Human ARTN/Artemin Protein, N-His (HP433012) expressed in E. coli, spanning Ala108-Gly220. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q5T4W7
Protein length	Ala108-Gly220
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	14.41 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	ARTN, Artemin, EVN, Enovin, Neublastin
Background	Artemin is a ~22 kDa protein. Growth factor that supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Acts by binding to its coreceptor, GFRA3, leading to autophosphorylation and activation of the RET receptor. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. 1. Masure, S. et al. (1999) European journal of biochemistry 266, 892-902. PMID: 10583383 2. Baloh, RH. et al. (1998) Neuron 21, 1291-302. PMID: 9883723 3. Li, J. et al. (2019) eLife 8. PMID: 31535977
Note	For research use only

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Datasheet

Human ARTN/Artemin Recombinant Protein (N-His).pdf

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Human ARTN/Artemin Recombinant Protein (N-His) (HP433012)

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