

| Número de catálogo | HX250065 |
|---|---|
| Descripción |
Anti-Human B2M Monoclonal Antibody (1A063) [1A063] (HX250065) is a mouse monoclonal antibody detecting B2M in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, IHC, WB |
| Especie huésped | Mouse |
| Clonalidad | Monoclonal |
| Isotipo | IgG1 |
| ID de clon | 1A063 |
| Inmunógeno | Mammalian cells - derived recombinant Human B2M (Met1-Met119). |
| Objetivo | Beta-2-microglobulin, B2M, |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >95% as determined by SDS-PAGE. |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | P61769 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Fondo | Beta-2-microglobulin (B2M/β2-MG) is a ~13 kDa protein. Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation. 1. Sreejit, G. et al. (2014) PLoS pathogens 10, e1004446. PMID: 25356553 |
| Nota | For research use only. |

SDS-PAGE for Anti-Human B2M Monoclonal Antibody (1A063)




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