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Anti-Human beta 2-Microglobulin Monoclonal Antibody (1A052) (HX250035)

Anti-Human beta 2-Microglobulin Monoclonal Antibody (1A052)
Anti-Human beta 2-Microglobulin Monoclonal Antibody (1A052)
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Overview
Catalog No.HX250035
Description
Anti-Human B2M/β2-MG Antibody (1A052) [1A052] (HX250035) is a mouse monoclonal antibody detecting B2M in ELISA (Cap), GICA (Cap), CLIA (Cap). Suitable for Human.
Highlights
  • ●Multi-Application — Validated across multiple applications.
Species reactivityHuman
ApplicationsELISA (Cap), GICA (Cap), CLIA (Cap)
Host speciesMouse
ClonalityMonoclonal
IsotypeIgG
Clone ID1A052
Immunogen Human Beta-2-microglobulin Protein.
Target Beta-2-microglobulin, B2M
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P61769
Form Liquid
Storage buffer 0.01M PBS pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Beta-2-microglobulin (B2M/β2-MG) is a ~13 kDa protein. Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.

1. Sreejit, G. et al. (2014) PLoS pathogens 10, e1004446. PMID: 25356553
Note For research use only.
Images
  • Anti-Human beta 2-Microglobulin Monoclonal Antibody (1A052)

    SDS-PAGE

    SDS-PAGE for Anti-Human B2M/β2-MG Antibody (1A052)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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