

| Catalog No. | HX250065 |
|---|---|
| Description |
Anti-Human B2M Monoclonal Antibody (1A063) [1A063] (HX250065) is a mouse monoclonal antibody detecting B2M in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | ELISA, IHC, WB |
| Host species | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone ID | 1A063 |
| Immunogen | Mammalian cells - derived recombinant Human B2M (Met1-Met119). |
| Target | Beta-2-microglobulin, B2M, |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P61769 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Beta-2-microglobulin (B2M/β2-MG) is a ~13 kDa protein. Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation. 1. Sreejit, G. et al. (2014) PLoS pathogens 10, e1004446. PMID: 25356553 |
| Note | For research use only. |

SDS-PAGE for Anti-Human B2M Monoclonal Antibody (1A063)




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