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Anti-Human beta 2-Microglobulin Monoclonal Antibody (1A063) (HX250065)

Anti-Human beta 2-Microglobulin Monoclonal Antibody (1A063)
Anti-Human beta 2-Microglobulin Monoclonal Antibody (1A063)
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Aperçu
Numéro de catalogueHX250065
Description
Anti-Human B2M Monoclonal Antibody (1A063) [1A063] (HX250065) is a mouse monoclonal antibody detecting B2M in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Recombinant — Superior batch-to-batch reproducibility with defined sequences.
  • ●Multi-Application — Validated across multiple applications.
Reactivité des espècesHuman
ApplicationsELISA, IHC, WB
Espèce hôteMouse
ClonalitéMonoclonal
IsotypeIgG1
ID de clone1A063
Immunogène Mammalian cells - derived recombinant Human B2M (Met1-Met119).
Cible Beta-2-microglobulin, B2M,
Niveau d'endotoxines Please contact with the lab for this information.
Pureté >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P61769
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Beta-2-microglobulin (B2M/β2-MG) is a ~13 kDa protein. Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation.

1. Sreejit, G. et al. (2014) PLoS pathogens 10, e1004446. PMID: 25356553
Note For research use only.
Images
  • Anti-Human beta 2-Microglobulin Monoclonal Antibody (1A063)

    SDS-PAGE

    SDS-PAGE for Anti-Human B2M Monoclonal Antibody (1A063)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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